翻訳と辞書 Words near each other ・ Diego Alessi ・ Diego Alfredo Molero Bellavia ・ Diego Allona ・ Diego Alonso ・ Diego Alonso Hinojosa Aguerrevere ・ Diego Alvarez (character) ・ Diego Alves ・ Diego Amozurrutia ・ Diego and Glot ・ Diego and His Brothers ・ Diego Andrada de Payva ・ Diego Andrade Silva Bispo ・ Diego Andrei Mejía ・ Diego Andrés Bermúdez ・ Diego Angulo Íñiguez ・ Diego antigen system ・ Diego Antonio Reyes ・ Diego Antón ・ Diego Aracena International Airport ・ Diego Aranega ・ Diego Archuleta ・ Diego Arias ・ Diego Arias de Miranda ・ Diego Arismendi ・ Diego Armando Basto ・ Diego Armando Causado ・ Diego Arria ・ Diego Aráoz ・ Diego Assis ・ Diego Augusto Teixeira Alves Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Diego antigen system ： ウィキペディア英語版 Diego antigen system The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1). The antigens are inherited through various alleles of the gene SLC4A1 (Solute carrier family 4), located on human chromosome 17. The AE1 glycoprotein is expressed only in red blood cells and, in a shortened form, in some cells in the kidney. The Diegoa antigen is fairly common in Indigenous peoples of the Americas (in both North and South America) and East Asians, but very rare or absent in most other populations, supporting the theory that the two groups share common ancestry. ==Types== The Diego system is named after a pair of types, Diegoa (Dia) and Diegob (Dib), which differ by one amino acid in the AE1 glycoprotein, corresponding to one difference in the nucleotide sequence of the SLC4A1 gene. Dib is common or ubiquitous in all populations which have been screened for it, while Dia has been found only in Indigenous peoples of the Americas (in both North and South America) and East Asians, and in people with some ancestors from those groups. People heterozygous for the two alleles produce both antigens. No individual has been tested who does not produce one, or both, of the two antigens. Anti-Dia (the antibody to Dia) can cause severe hemolytic disease of the newborn and severe transfusion reaction. Anti-Dib usually causes milder reactions. The Wright blood system is another pair of types, Wrighta (Wra) and Wrightb (Wrb), also differing by one amino acid on the AE1 glycoprotein and one nucleotide on the SLC4A1 gene. Wra always expresses antigens, but the antibody reaction of Wrb depends on a variation in the structure of glycophorin A, which binds with Wrb. Anti-Wra can also cause severe hemolytic disease of the newborn and severe transfusion reaction. Anti-Wrb is very rare, and little data is available on its severity.〔 Seventeen other rare blood types (as of 2002) are included in the Diego antigen system, as they are produced by mutations on the SLC4A1 gene. These include the Waldner (Wda), Redelberger (Rba), Warrior (WARR), ELO, Wulfsberg (Wu), Bishop (Bpa), Moen (Moa), Hughes (Hua), van Vugt (Vga), Swann (Swa), Bowyer (BOW), NFLD, Nunhart (Jna), KREP, Traversu (Tra), Froese (Fra) and SW1 types. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Diego antigen system」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.